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Neoprene, homopolymer of chlorobutadiene (CR), is moderately resistant to both petroleum oils and weather (ozone, UV, oxygen). Neoprene is classified as a general purpose elastomer which has relatively low compression set, good resilience and abrasion, and is flex cracking resistant. Neoprene has excellent adhesion qualities to metals for rubber to metal bonding applications. It is used extensively for sealing refrigeration fluids due to its excellence resistance to Freon® and ammonia.

Neoprene is suitable for dynamic and static seal of o-rings in the environment containing the following chemicals: Acetamide, Acetic Anhydride, Acetylene Gas, Acrylonitrile, Aluminium Chloride, Aluminium Flouride, Aluminium Nitrate, Aluminium Sulfate, Anhydrous Ammonia, Cold Gas Ammonia, Ammonium Carbonate, Ammonium Chloride, Concentrated Ammonium Hydroxide, Ammonium Nitrate, Ammonium Phosphate, Ammonium Sulfate, Amyl Alcohol, Amyl Borate, ASTM Oil One, ASTM Oil Two, Benzoic Acid, Borax Solutions, Boric Acid, Butyl Alcohol, Calcium Carbonate, Calcium Chloride, Calcium Hydroxide, Calcium Nitrate, Calcium Sulfide, Carbon Monoxide, Castor Oil, Tung Oil China Wood Oil, Chloracetic Acid, Citric Acid, Coffee, Denatured Alcohol, Diethylamine Glycol, Dow Corning 550, Dow Guard, Epoxy Resins, Ethanol, Ethyl Alcohol, Ethyl Diamine, Ethyl Hexanol, Ethyl Silicate, Ethylene Glycol, Freon 113, Freon 114, Freon 114B2, Freon 13, Freon 22, Freon 31, Freon 32, Freon 502 (F22+F316), Freon C318, Freon TF, Gelatine, Glycerin, General Glycol, Helium, Hydrogen Gas, Iso Octane, Isobutyl Alcohol, Linsed Oil, Lye, Mercuric Chloride, Mercury, Methanol, Milk, MIL-S-81087, Mineral Oils, Natural Gas, N-Hexaldehyde, Gas Nitrogen, N-Pentane, Oronite 8200, Cold Oxygen, Petroleum Oil, Potassium Nitrate, Potassium Sulfate, Propanol, Propyl Alcohol, Silicone Grease, Silicone Oils, Silver Nitrate, Sodium Bicarbonate, Sodium Carbonate, Sodium Chloride, Sodium Hydroxide, Soyabean Oil, Sucrose Solutions, Sulfur Hexafluoride, Tannic Acid, Tartaric Acid, Whiskey.

O-Ring material Neoprene is usually suitable for static seal in the environment containing Glacial Acetic Acid, Aluminium Acetate, Hot Gas Ammonia, Animal Oil, ASTM Fuel A, Automatic Transmission Fluid, Automotive Brake Fluid, Beer, Benzene Sulfonic Acid, Butter, Carbonic Acid, Cod Liver Oil, Coolanol Monsanto, Diethylamine, Ethane, Ethyl Cellulose, Ethyl Formate, Freon 112, Fuel Oil, Gallic Acid, Glucose, Heptane, Hexane, Hexyl Alcohol, Petroleum Base Hydraulic Oil, Hydrazine, Hydrocyanic Acid, Hydrogen Peroxide, Isopropanol, Animal Fat Lard, Petroleum Base Lubricating Oils, Methane, Methyl Alcohol, Methyl Cellosolve, Methylacrylic Acid, MIL-F-25558 (RJ-1), MIL-G-25760, MIL-H-5606, MIL-H-7083, MIL-L-25681, Octyl Alcohol, Oxalic Acid, Ozone, Producer Gas, Transformer Oil Pyranol, Rapeseed Oil, RJ-1 (MIL-F-25558), Sea Water, Stearic Acid, Wet Sulfur Dioxide Gas, Sulfurous Acid, Tertiary Butyl Alcohol, Tetrabutyl Titanate, Type A Transmission Fluid, Turbine Oil, Vinegar, VV-H-910, Wagner 21B Brake Fluid, Fresh Water.

O-Ring material Neoprene is sometimes ok for static seal but not for dynamic seal in the environment containing chemicals such as ASTM Oil Three, Butyl Carbitol, Calcium Hypochlorite, Carbitol 2, Chlordane, Crude Oil (Asphalt Base), Elco 28 Lubricant, Kerosene, Methyl Ether, MIL-R-25576 (RP-1), Nitroethane, Oleic Acid, Propane, Radiation, Red Oil, RP-1 (MIL-R-25576), Stoddard Solvent, Tetraethyl Lead.

Neoprene is not suitable for o-rings exposed in the environment containing chemicals such as Acetaldehyde, Acetone, Acetophenone, Acetyl Chloride, Air below 200 C, Alkazene, Amyl Acetate, Amyl Chloronaphthalene, Aniline Oil, Arachlor 1248, Argon, Aromatic Fuel 50%, Askarel Transformer Oil, ASTM Fuel B, ASTM Fuel C, ASTM Fuel D, ASTM Oil Four, Benzaldehyde, Benzene, Benzyl Chloride, Brake Fluid, Bromine Gas, Bromobenzene, Butyl Cellosolve, Carbolic Acid (Phenol), Carbon Disulfide, Carbon Tetrachloride, Cellosolve, Chlorinated Solvents, Chlorine Dioxide, Chlorine Trifluoride, Dry Chlorine, Wet Chlorine, Chloroform, Chlorosulfonic Acid, Chrome Plating Solution, Chromic Acid, Creosylic Acid, Cyclohexane, Diacetone, Dibenzyl Ether, Dibutyl Phthalate, Dichloro-Butane, Di-ester Lubricant MIL-L-7808, Dimethyl Formamide, Dimethyl Phthalate, Dioxane, Diphenyl, Dowtherm A, Ethyl Benzene, Ethyl Benzoate, Ethyl Chloride, Ethyl Chlorocarbonate, Ethyl Ether, Ethyl Oxalate, Ethyl Pentachlorobenzene, Ethylene Dichloride, Ethylene Oxide, Ethylene Trichloride, Formaldehyde, Freon 11 (M), Furan, Furfuryl Alcohol, Automotive Gasoline, Hydrochloric Acid, Hydroquinone, Iodine, Isopropyl Acetate, Isopropyl Chloride, Isopropyl Ether, JP 3 MIL-J5624, JP 4 MIL-J5624, JP 5 MIL-J5624, JP 6 MIL-J5624, Lacquer Solvents, Lacquers, Hydraulic Fluid (Phosphate Ester Type) Lindol, Maleic Acid, Methyl Acrylate, Methyl Bromide, Methyl Butyl Ketone, Methyl Chloride, Methyl Ethyl Ketone (MEK), Methyl Isobutyl Ketone (MIBK), Methyl Methacrylate, Methyl Oleate, Methyl Propyl Salicylate, Methylene Chloride, MIL-F-25656, JP-5 JP-4 JP-3 MIL-J 5624, Monovinyl Acetate, Naphtha, Naphthalene, Naphthalenic, Neatsfoot Oil, Nitrobenzene, Nitrogen Tetroxide, Nitromethane, Nitropropane, N-Octane, Oleum (Fuming Sulfuric Acid), 200-400F Oxygen, Phenol, Phenylhydrazine, Phosphoric Acid, Phosphoric Trichloride, Pine Oil, Propyl Acetate, Propylene, Propylene Oxide, 10E Pydraul, 540C 312F 230C Pydraul, 90E 65E 50E 30E Pydraul, 55 (Phosphate Ester) 53 43 Pyrogard 42, Skydrol 500, Styrene Monomer, Sulfur Chloride, Dry Sulfur Dioxide Gas, Liquefied Under Pressure Sulfur Dioxide, Sulfur Trioxide, Tertiary Butyl Mercaptan, Tetrabromoethane, Tetrachloroethane, Tetrachloroethylene, Tetrahydrofuran, Tetralin, Toluene, Triethanolamine, Turpentine, Varnish, White Pine Tar, Xylene.